Ulwazi Oluyisisekelo:
Igama Lomkhiqizo: I-Bitter Almond Extract formula yemolekyuli: C20H27NO11
I-solvent yokukhipha: I-Ethanol namanzi Isisindo se-molecular: 457.42
Izwe Imvelaphi: I-China Irradiation: Ayinamisebe
Ukuhlonza: TLC GMO: Non-GMO
Inkampani Yenethiwekhi/Abasizi: Ayikho I-HS CODE: 1302199099
I-Amygdalin itholakala ikakhulukazi kubhilikosi, i-almond, ipentshisi, i-nectarine, i-loquat, iplamu, i-apula, i-cherry emnyama namanye amantongomane namaqabunga.I-Amygdalin ayikho esikhumbeni se-amygdalin.
Umsebenzi:
1. umphumela we-amygdalin ku-cardiovascular
2. umphumela we-amygdalin ohlelweni lokugaya ukudla
1) I-Anti Gastric ulcer: imiphumela ye-amygdalin ekuhlolweni kwesilonda sesisu yabonwa ngokusungula imodeli yamagundane aboshwe ingcindezi eqandisiwe isilonda esiswini, imodeli yezilonda ezivuthayo i-acetic kanye nemodeli yesilonda sesisu samagundane sokuxhunywa kwe-pylorus.Imiphumela yabonisa ukuthi iqembu le-20 kanye ne-40 mg / kg ye-amygdalin lingavimbela ukucindezeleka okubophezelayo okubopha isilonda sesisu kumagundane;5. Amaqembu angu-10 no-20 mg/kg angakhuthaza ukuphulukiswa kwesilonda;10. Indawo yesilonda yesilonda esiswini esibangelwa i-pylorus ligation yehliswa ngeqembu lama-20 mg/kg, okuphakamisa ukuthi i-amygdalin inomphumela ongcono wokulwa nezilonda.
2) I-Liver fibrosis: imodeli ye-bleomycin yasungulwa ngendlela yokuchayeka kuqhoqhoqho.I-Amygdalin 15 mg/kg yajova nge-intraperitoneally ukuze iphenye umphumela wayo ekuvezeni i-collagen I no-III kumagundane e-bleomycin.Ngosuku lwe-7, lwe-14 nolwe-28 lokumodela, iphesenti lendawo yohlobo lwe-collagen III eqenjini le-amygdalin laliphansi kunalelo leqembu le-bleomycin, futhi iphesenti lendawo ye-collagen yohlobo lwe-I kuzicubu zamaphaphu zeqembu le-amygdalin lehla ngosuku lwama-28.Kwaphakanyiswa ukuthi i-amygdalin ingavimbela ukwakheka kwe-collagen I no-III, futhi ibambezele ngokuphumelelayo inqubo ye-pulmonary fibrosis kumagundane okuhlola, iphakamisa ukuthi umuthi ungasetshenziswa ekuvimbeleni nasekwelapheni i-human pulmonary fibrosis.
3. umthelela we-amygdalin ohlelweni lokuchama: imodeli ye-renal interstitial fibrosis yasungulwa ngokuvinjwa kwe-ureter unilateral.Amagundane anikezwe i-3, i-5 mg / D nge-gavage eqenjini le-amygdalin, futhi izilwane zabulawa izinsuku ezingu-7,14,21 ngemuva kokuhlinzwa, futhi ukulimala kwezinso zezinso eqenjini ngalinye kwabonwa.Imiphumela yabonisa ukuthi izinga le-renal fibrosis leqembu le-amygdalin laliphansi kakhulu kunalelo leqembu elihlangene elihlangene lokuvinjelwa kwe-urethra ezinsukwini ezingu-21, lapho iqembu lokwelapha lika-3 mg / D lehla ngo-35%, futhi iqembu lokwelapha lika-5mg / D lehla. ngo-28%.Kwaboniswa ukuthi i-amygdalin ngokusobala inganciphisa izinga lokulimala kwe-renal pathological futhi ibambezele inqubo ye-renal interstitial fibrosis, futhi yafakazela futhi ukuthi i-amygdalin inomphumela wokulwa ne-fibrosis;
4. umphumela we-amygdalin kumasosha omzimba
5. umphumela we-ntitumor we-amygdalin: 1.25 kuya ku-10g/L i-amygdalin kumaseli omdlavuza wesinye (UMUC-3, RT112, TCCSUP) izikhathi ezi-3 ngesonto, amaviki angu-2 kamuva athola ukuthi umthamo oncike ku-amygdalin wokuvinjelwa kwe-tumor cell ukukhula nokuzala, ukuze i-stagnate esigabeni se-G0/G1, kanye no-10 g/L lapho umphumela omuhle kakhulu.Ikhono lokufuduka kanye nokunamathiselwe kwe-muc-3 ne-RT112 lehle kakhulu ngaphansi kwesenzo se-10 g / L amygdalin, kodwa amandla okufuduka e-tccsup anda, okuphakamisa ukuthi i-amygdalin ingalawula i-integrin β 1 noma β 4, ithinta okunamathiselwe nokufuduka. yamangqamuzana omdlavuza wesinye, futhi umphumela wawo uhlobene nohlobo lwamaseli.
6. umphumela we-amygdalin ohlelweni lokuphefumula
Imininingwane yokupakisha:
Ukupakisha kwangaphakathi: Isikhwama se-PE esiphindwe kabili
Ukupakisha kwangaphandle: Isigubhu (Isigubhu sephepha noma isigubhu seringi yensimbi)
Isikhathi sokulethwa: Phakathi nezinsuku ezingu-7 ngemva kokuthola inkokhelo
Udinga umenzi wezingcaphuno zezitshalo ochwepheshile, sisebenze kulo mkhakha iminyaka engaphezu kwengu-20 futhi sinocwaningo olunzulu ngawo.
Umkhiqizo Wokunakekelwa Kwezempilo, Izithasiselo Zokudla, Izimonyo
